定量组织速度成像评价扩张型心肌病患者的左心室旋转收缩功能

目的 探讨应用定量组织速度成像（QTVI）技术评价扩张型心肌病（DCM）患者左心室旋转收缩功能的价值。方法 获取15例DCM患者与17例正常人的标准左心室二尖瓣水平、心尖水平短轴切面TVI图像，应用QTVI技术离线分析室间隔、侧壁、前间隔、后壁处心肌组织速度曲线，应用公式计算收缩期左心室二尖瓣水平、心尖水平旋转和左心室扭转；应用二维超声心动图双平面Simpson方法计算左心室射血分数（LVEF）。结果 与正常人相比，DCM患者收缩期左心室二尖瓣水平、心尖水平旋转和左心室扭转均显著降低。DCM患者收缩期左心室二尖瓣水平、心尖水平旋转和左心室扭转与LVEF均有较好的相关性。结论 DCM患者的左心室旋转收缩功能显著受损，QTVI技术评价的左心室旋转收缩功能是准确反映左心室收缩功能的超声新指标。

Evaluation of Left Ventricular Rotational Contraction Function in Patients with Dilated Cardiomyopathy via Quantitative Tissue Velocity Imaging

Objective To evaluate left ventricular rotational contraction function in patients with dilated cardiomyopathy(DCM)via quantitative tissue velocity imaging(QTVI).Methods TVI images of left ventricle were aquired at apical and basal short-axis levels in 15 patients with DCM and 17 healthy subjects,offline left ventricular velocity profiles of septal,lateral,anteroseptal and posterior sites were obtained synchronously on QTVI,and left ventricular systolic rotation at apical and basal short-axis levels and left ventricular torsion were calculated by formulae.LVEF was obtained by two-dimensional echocardiography using Simpson rule.Results Compared with healthy subjects,left ventricular systolic rotation of apical and basal short-axis levels and left ventricular systolic torsion in patients with DCM were significantly lower than that of the control.In patients,there was a statistically significant correlation between left ventricular systolic rotation of apical and basal short-axis levels and left ventricular systolic torsion as well as LVEF.Conclusions Left ventricular rotational contraction function in patients with DCM was significantlly impaired,Based on our study,QTVI is a new method for evaluating left ventricular contraction function.