| 狗牙根的化学成分研究 |
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| 引用本文： | 李碧君,刘瑶,顾爱彤,王峰.狗牙根的化学成分研究[J].中草药,2017,48(1):62-66. |
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| 作者姓名： | 李碧君 刘瑶 顾爱彤 王峰 |
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| 作者单位： | 广东药科大学中药学院, 广东 广州 510006;国家中医药管理局中药数字化质量评价技术重点研究室, 广东 广州 510006;广东高校中药质量工程技术研究中心, 广东 广州 510006;广东药科大学中药学院, 广东 广州 510006;国家中医药管理局中药数字化质量评价技术重点研究室, 广东 广州 510006;广东高校中药质量工程技术研究中心, 广东 广州 510006;广东药科大学中药学院, 广东 广州 510006;国家中医药管理局中药数字化质量评价技术重点研究室, 广东 广州 510006;广东高校中药质量工程技术研究中心, 广东 广州 510006;广东药科大学中药学院, 广东 广州 510006;国家中医药管理局中药数字化质量评价技术重点研究室, 广东 广州 510006;广东高校中药质量工程技术研究中心, 广东 广州 510006 |
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| 基金项目： | 国家自然科学基金项目（81202884） |
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| 摘 要： | 目的研究狗牙根Cynodon dactylon全草的化学成分。方法采用各种柱色谱方法对狗牙根化学成分进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果从狗牙根95%乙醇提取物的醋酸乙酯萃取部位中分离得到12个芪类二聚体,分别鉴定为leachianol G(1)、leachianol F(2)、parthenostilbenin B(3)、parthenostilbenin A(4)、restrytisol B(5)、caraphenol C(6)、pallidol(7)、laetevirenol A(8)、quadrangularin B(9)、quadrangularin C(10)、quadrangularin A(11)、parthenocissine A(12)。结论化合物1~12为首次从狗牙根属植物中分离得到。
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| 关 键 词： | 狗牙根 芪类二聚体 leachianol G parthenostilbenin B restrytisol B caraphenol pallidol |
| 收稿时间： | 2016/7/20 0:00:00 |
Chemical constituents of Cynodon dactylon |
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| LI Bi-jun,LIU Yao,GU Ai-tong and WANG Feng.Chemical constituents of Cynodon dactylon[J].Chinese Traditional and Herbal Drugs,2017,48(1):62-66. |
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| Authors: | LI Bi-jun LIU Yao GU Ai-tong and WANG Feng |
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| Institution: | School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China;Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, Guangzhou 510006, China;Engineering & Technology Research Center for Chinese Materia Medica Quality of the Universities of Guangdong Province, Guangzhou 510006, China;School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China;Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, Guangzhou 510006, China;Engineering & Technology Research Center for Chinese Materia Medica Quality of the Universities of Guangdong Province, Guangzhou 510006, China;School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China;Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, Guangzhou 510006, China;Engineering & Technology Research Center for Chinese Materia Medica Quality of the Universities of Guangdong Province, Guangzhou 510006, China;School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China;Key Laboratory of Digital Quality Evaluation of Chinese Materia Medica of State Administration of TCM, Guangzhou 510006, China;Engineering & Technology Research Center for Chinese Materia Medica Quality of the Universities of Guangdong Province, Guangzhou 510006, China |
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| Abstract: | Objective To separate and identify chemical constituents from Cynodon dactylon. Methods The chemical constituents of the alcohol extract of C. dactylon were isolated and purified by various chromatography methods, and their structures were identified by physical and chemical properties and spectral data. Results Twelve compounds were separated from C. dactylon and their structures were examined by physicochemical characters and spectral data and identified as leachianol G (1), leachianol F (2), parthenostilbenin B (3), parthenostilbenin A (4), restrytisol B (5), caraphenol C (6), pallidol (7), laetevirenol A (8), quadrangularin B (9), quadrangularin C (10), quadrangularin A (11), and parthenocissine A (12). Conclusion Compounds 1-12 are isolated from C. dactylon for the first time. |
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| Keywords: | Cynodon dactylon (L ) Pars Stilbene dipolymer leachianol G parthenostilbenin B restrytisol B caraphenol pallidol |
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