针药并用治疗甲状腺功能亢进性突眼症临床效应观察

目的观察针药并用治疗甲亢性突眼症的临床效应,为甲亢性突眼症的治疗提供更为有效的选择。方法将52例患者（计104只眼）随机分为针药组（27例,54只眼）和西药组（25例,50只眼）,针药组采用针刺配合甲巯咪唑10mg/d和左甲状腺素钠片25μg/d,西药组仅予甲巯咪唑10mg/d和左甲状腺素钠片25μg/d。通过比较两组患者突眼度的改善,观察针刺加西药治疗甲亢性突眼症的临床效应。结果针药组总有效率为96.3%,西药组为64.0%,针药组优于西药组（P〈0.01）。两组间突眼度治疗前后减少差值比较,针药组突眼度减少（1.88±1.409）mm,明显大于西药组（0.72±0.757）mm（P〈0.01）。结论针药并用可有效改善患者眼球突出度。

Observations on the Clinical Efficacy of Combined use of Acupuncture and Drugs in Treating Hyperthyroid Exophthalmos

Objective To investigate the clinical efficacy of combined use of acupuncture and drugs in treating hyperthyroid exophthalmos and provide a more effective treatment for hyperthyroid exophthalmos. Methods Fifty-two patients were randomly allocated to an acupuncture-drug group of 27 （54 eyes） cases and a western drug group of 25 （50 eyes） cases. The acupuncture-drug group received acupuncture plus methimazole 10 mg/d and levothyroxine sodium 25 g/d and the western drug group took methimazole 10 mg/d and levothyroxine sodium 25 g/d only. The clinical therapeutic effect of combined acupuncture and western drugs on hyperthyroid exophthalmos was investigated by a comparison of the improving effects on exophthalmos between the two groups of patients. Results The total efficacy rate was 96.3% in the acupuncture-drug group and 64.0% in the western drug group. The effect was better in the acupuncture-drug group than in the western drug group （P〈0.01）. A comparison of pre-/post-treatment decreases in the extent of eyeball protrusion between the two groups showed that a decrease of 1.88±1.409 mm in the acupuncture-drug group was significantly larger than a decrease of 0.72±0.757 mm in the western drug group （P〈0.01）. Conclusion Combined use of acupuncture and drugs can effectively reduce the extent of eyeball protrusion in the patients.