不同营养方式对肝移植术后临床恢复的影响

目的探讨不同营养方式对肝移植患者术后恢复的影响。方法用随机数排序分组法将2005年10月~2006年12月实施原位肝移植术的42例患者随机分为肠内营养(EN)组和全胃肠外营养(TPN)组,各21例。比较两组患者术后肝功能及营养指标、营养费用、术后住院时间、感染率、死亡率、胃肠道功能恢复情况、胃肠道并发症。结果EN组肝移植术后肝功能恢复较好;感染率、营养费用明显低于TPN组;胃肠道功能恢复时间、术后住院时间较TPN组短,两组比较差异有显著性意义,P<0.05或P<0.01。营养指标、死亡率、胃肠道并发症两组差异无显著性意义,P>0.05。结论肝移植术后早期应用EN能促进患者的临床恢复。

Study on the effects of post-operative recovery by different nutritional therapies for patients undergoing liver transplantation

Objective To investigate the effects of different nutritional therapies on clinical recovery of patients after liver transplantation. Method A randomized clinical trial was conducted comparing the role of enteral nutrition group with total parenteral nutrition group in 42 patients after orthotopic liver transplantation from October 2005 to December 2006,each group has 21 cases.The liver function and nutritional parameter,nutritional expenses,the length of hospitalization,the incidence of infection,mortality,recovery times of gastrointestinal function,gastrointestinal complications were compared between the two groups.Result The liver function for patients undergoing enteral nutrition was significantly better than that of total parenteral nutrition group.The incidence of infection,nutritional expenses,recovery times of gastrointestinal function,length of hospitalization were lower in enteral nutrition group.The length of hospitalization were shorter,there were significant difference between the two groups(P<0.05 or P<0.01).There were no significant difference in nutritional parameter,mortality and gastrointestinal complications between the two groups(P>0.05).Conclusion Enteral nutrition can improve the rehabilitation of patients undergoing liver transplantation.