| 获得性异位骨化的研究进展 |
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| 引用本文： | 胡洋洋,卢海妹,刘亚坤,姜玉,阚立新. 获得性异位骨化的研究进展[J]. 基础医学与临床, 2017, 37(11). DOI: 10.3969/j.issn.1001-6325.2017.11.028 |
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| 作者姓名： | 胡洋洋 卢海妹 刘亚坤 姜玉 阚立新 |
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| 作者单位： | 1. 安徽医科大学基础医学院病理生理学教研室,安徽合肥,230032;2. 安徽医科大学基础医学院病理生理学教研室,安徽合肥230032;西北大学神经学系, 美国芝加哥60611 |
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| 摘 要： | 获得性异位骨化(aHO)是指正常骨骼系统之外出现的异常骨组织。aHO的创伤来源丰富且病因复杂,BMP信号通路、Hedgehog信号通路、Wnt/β-catenin信号通路和NF-κB信号传导通路在aHO的致病过程中发挥重要作用。
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| 关 键 词： | 获得性异位骨化 信号通路 致病机制 |
Progress in the research of acquired heterotopic ossification |
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| HU Yang-yang,LU Hai-mei,LIU Ya-kun,JIANG Yu,KAN Li-xin. Progress in the research of acquired heterotopic ossification[J]. Basic Medical Sciences and Clinics, 2017, 37(11). DOI: 10.3969/j.issn.1001-6325.2017.11.028 |
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| Authors: | HU Yang-yang LU Hai-mei LIU Ya-kun JIANG Yu KAN Li-xin |
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| Abstract: | Acquired heterotopic ossification is the abnormal bone formation outside of the normal skeletal system . The origin trauma and disease of aHO is plentiful .In this paper, we reviewed on BMP ,hedgehog,wnt/β-catenin and NF-κB signaling pathway , understanding of the pathogenesis of aHO . |
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| Keywords: | acquired heterotopic ossification signaling pathway pathogenesis |
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