乳腺癌组织类型的动态增强MRI鉴别诊断

目的 探讨乳腺动态增强MRI在不同病理类型乳腺癌鉴别诊断中的价值.方法 回顾性分析45例经病理证实的乳腺癌患者MRI资料,所有患者术前均行动态增强MRI,绘制时间-信号强度曲线,计算不同时期强化率,并用单因素方差分析进行统计学分析.结果 45例乳腺癌中,29例为浸润性导管癌,6例为黏液腺癌,4例乳头状癌,4例浸润性筛状...

Histopathological types of breast differentiated by the dynamic contrast-enhanced magnetic resonance imaging

Objective To demonstrate the features of different breast carcinomas by DCE-MRI.Methods Using a retrospectively database,45 patients with breast carcinoma surgicopathology were conducted.All patients underwent dynamic enhanced scanning.Time intensity curves（TICs） were obtained from the regions showing maximal enhancement in the enhanced images and classified as monophasic（typeⅠ）,biphasic（typeⅡ）,or washout（typeⅢ） according to their shapes.The enhancement rate of differential time was observed and compared by one-way analysis of variance（ANOVA）.Results There were 29 cases of the ductal carcinomas,6 cases of the mucinous carcinomas,4 cases of the papillary carcinomas,4 cases of the cribriform carcinomas and 2 cases of the medullary carcinomas.The maximum diameter of the lesions ranged from 1 to 8.1 cm.Of the 45 patients TICs were showed as type Ⅲ in 31 cases（68.9%）,type Ⅱin 9 cases（20.0%）,and type Ⅰ in 5 cases（11.1%）.A significant difference was found between the cribriform carcinoma and the mucinous carcinoma in the early enhancement rate.A significant difference was found between the cribriform carcinoma and the papillary carcinoma in the enhancement rate of the second and the third date.Conclusion DCE-MRI can offer additional morphological information about different breast carcinomas and improve our ability to differentiate the histopathological type of breast carcinoma.