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A clinical case of neuro-Behçet syndrome without mucocutaneo-ocular symptoms: Relationship with brain stem encephalitis
Authors:YOICHI KAWANISHI md  TAKAFUMI HORI md  TOSHIHITO SUZUKI md  KATSUYOSHI MIZUKAMI md  MEGUMI SASAKI md   HIROYASU SHIRAISHI md
Affiliation:Psychiatric Service, University of Tsukuba Hospital, and University of Tsukuba, Ibaraki, Japan;Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
Abstract:Abstract The case of a 50 year old man with personality changes, dementia, and brain stem symptoms is presented. Magnetic resonance imaging (MRI) disclosed high signal areas mainly in the brain stem. Both a positive skin prick test and an HLA-B51 were demonstrated. These clinical findings were suggestive of neuro-Behçet syndrome, although there were no mucocutaneo-ocular symptoms characteristically associated with this disease. The relationship between neuro-Behçet syndrome and brain stem encephalitis, including a discrimination from multiple sclerosis, is discussed.
Keywords:HLA-B51    multiple sclerosis    skin prick test.
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