In Vitro Cytotoxicity of Nanoparticles in Mammalian Germ-Line Stem Cell

Nanotechnology involves the creation and manipulation of materialsat nanoscale levels to create products that exhibit novel properties.There are important applications of nanoscience in biology andbiotechnology, and nanotechnology offers new tools to biologists(Whitesides, 2003). Nevertheless, despite the increased interest in the developmentof nanoparticles, few studies address their potential toxicity.The rapidly developing field of nanotechnology is likely tobecome yet another source of human exposure to nanoparticlesby different routes: inhalation, ingestion, dermal, and injection.Regulatory agencies, researchers, and health and environmentalwatchdogs are assessing how nanoscale materials affect humanhealth and the environment (Service, 2004). Similarly, the characteristic biokinetic behavior of nanoparticles