| 急性坏死性胰腺炎血液流变学改变及其意义 |
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| 引用本文： | 王自法,潘承恩,刘绍诰,梁国光,张梅.急性坏死性胰腺炎血液流变学改变及其意义[J].中国普通外科杂志,2000,9(3):225-227. |
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| 作者姓名： | 王自法 潘承恩 刘绍诰 梁国光 张梅 |
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| 作者单位： | 1. 西安医科大学第一附属医院,肝胆外科,陕西,西安,710061
2. 西安医科大学第一附属医院,中西医结合研究所,陕西,西安,710061 |
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| 摘 要： | 目的 研究急性坏死性胰腺炎（ＡＮＰ）血液流变学改变及其在病情演进中的作用。方法 检测ＡＮＰ大鼠的血液流变学指标。红细胞生及胰腺病理学检查。结果 ＡＮＰ大鼠全血粘度，血浆粘度，红细胞压积均显著升高，红细胞徨增加；纤维蛋白原降低。结论 ＡＮＰ时，出现显著血液流变学改变，后者可能是脂腺进行性坏死，病情恶化的主要原因之一。
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| 关 键 词： | 胰腺炎 病理生理学 血液汉变学 急性病 |
| 修稿时间： | 1999-03-18 |
The significance of hemorrheologic alternation in acute necrotizing pancreatitis |
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| WANG Zi-fa,PAN Cheng-en,LIU Shao-gao,LIANG Guo-guang,ZHANG Mei.The significance of hemorrheologic alternation in acute necrotizing pancreatitis[J].Chinese Journal of General Surgery,2000,9(3):225-227. |
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| Authors: | WANG Zi-fa PAN Cheng-en LIU Shao-gao LIANG Guo-guang ZHANG Mei |
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| Abstract: | Objective To study the hemorrheologic alternation in acute necrotizing pancreatitis(ANP) and its effect in deterioating of ANP. Methods Blood samples were obtained from ANP rats for hemorrheologic examination and erythrocyte osmotic fragility test. Pancreatic tissue was obtained for pathological study. Results Blood viscosity, plasma viscosity, hematocrit, erythrocyte osmotic fragility were significantly elevated, while erythrocyte sedimentation rate and fibrinogen were decreased significantly in ANP rats compared with sham operation group. Conclusions In ANP rats, hemorrheology is altered significantly, which may be one of the important factors in deterioraton the disease. |
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| Keywords: | PANCREATITIS/physiopathol ?HEMORRHEOLOGY ?ACUTE DISEASE ?PANCREATITIS/pathol ?NECROSIS |
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