化疗性栓塞联合CT导引下射频消融治疗肝癌的临床价值

目的探讨化疗性栓塞（TACE）后联合CT引导下射频消融术（RFA）综合治疗肝癌的效果。方法选取2008年7月至2011年2月在襄阳市中医医院就诊的肝癌患者45例，根据单双日法的分组原则分为联合治疗组（20例）和TACE组（25例）。评估治疗后两组患者肿瘤坏死程度、甲胎蛋白（AFP）、肿瘤初次复发率、1年和2年生存率。结果联合治疗组治疗效果优于TACE组，二者比较差异有统计学意义（P〈0．05）；联合治疗组1年和2年生存率（95％和70％）均显著高于TACE组（60％和40％），而初次复发率（10％）明显低于TACE组（48％），比较差异有统计学意义（P〈0．05）。结论TACE联合CT引导下RFA是一种治疗肝癌安全、有效的方法，其疗效优于单纯TACE。

Combination of Transcatheter Arterial Chemoembolization and CT-guided Radiofrequency Ablation in Treating Liver Cancer

Objective To discuss the effect of transcatheter arterial chemoembolization （TACE） combined with CT guided by radio frequency ablation （ RFA ） as a comprehensive treatment for liver cancer. Methods According to principle of odd or even ,45 patients from Xiangyang Hospital of Traditional Chinese Medicine during July 2008 and February 2011 were selected and divided into two groups：combined therapy group（20 cases） and TACE group （25 cases）. The tumor necrosis degree, AFP index change, tumor recurrence rate and the one-year survival rate two-year survival rate were assessed. Results The combined therapy group was better than TACE group with significant differences（ P 〈 0.05 ）. One-year and two-year survival rate（95% and 70% ） of combined therapy group were both higher than that of TACE group （＇60% and 40% ） ,and the first relapse rate （ 10% ） was significantly lower than TACE group （ 48% ） （ P 〈 0.05 ）. Conclusion TACE combination with CT guided RFA is a safe and effective method for treating liver canc- er,with a better curative effect than the simple TACE.