Efficient design, synthesis and structure–activity relationship studies of 1-(3′-substituted propyl)-4-arylpiperidines as non-peptide antagonists of nociceptin/orphanin FQ receptor: biological activities, metabolic stabilities and hERG channel bindings |
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Authors: | Shigeo Hayashi Katsuyo Ohashi Eriko Nakata Chie Emoto |
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Institution: | 1. Nagoya Laboratories, Pfizer Global Research & Development, Pfizer Japan Inc., 5-2 Taketoyo, Aichi, 470-2393, Japan
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