2013—2019年上海市闵行区肺癌流行特征趋势分析

摘 要： ［目的］ 分析2013—2019年上海市闵行区户籍人口肺癌发病和死亡状况及其变化趋势。 ［方法］ 利用上海市2013—2019年肿瘤监测数据，计算闵行区不同性别、年龄人群肺癌发病和死亡率、标化发病和死亡率及早期诊断率等。标化率均以2000年全国人口普查标准人口及Segi世界标准人口年龄结构进行标化，记为中标率和世标率，并采用年度变化百分比（annual percentage change，APC）描述其变化趋势。 ［结果］ 2013—2019年闵行区肺癌发病率为95.64/10万，中标发病率为43.79/10万，世标发病率为42.95/10万；死亡率为56.30/10万，中标死亡率为21.04/10万，世标死亡率为20.93/10万。2013—2019年闵行区总人群和男性的肺癌发病率及其中标率、世标率APC差异均无统计学意义（P>0.05），女性发病率及其中标率、世标率均呈上升趋势，APC分别为10.30%、13.77%和12.64%（P<0.05）；男性、女性以及总人群的死亡率及其中标率、世标率均呈下降趋势，除男性中标死亡率外，趋势变化均有统计学意义（P<0.05）。发病率和死亡率均为男性高于女性，且均随年龄增长而显著升高（P<0.05）。总人群发病率峰值在80~84岁年龄组，死亡率峰值在85岁及以上年龄组。2013—2019年，肺癌新发诊断期别中早期占比从10.44%逐渐升高至16.98%。［结论］ 2013—2019年上海市闵行区肺癌发病率及其标化率无明显变化，死亡率及其标化率均呈下降趋势。发病和死亡主体为男性及老年人群，但女性和中年人群肺癌发病率上升趋势较快，新发诊断早期率仍较低，需引起重视并积极探索其原因。

Trend Analysis on Epidemiological Characteristics of Lung Cancer in Minhang District of Shanghai from 2013 to 2019

Abstract： ［Purpose］ To analyze the incidence and mortality of lung cancer in Minhang District of Shanghai from 2013 to 2019. ［Methods］ Using the data of lung cancer from Shanghai tumor surveillance system， the incidence and mortality of lung cancer， age-standardized incidence and mortality and early diagnosis rate of different gender and age groups in Minhang District were calculated. The age-standardized rates(ASRC， ASRW) were calculated according to the Chinese standard in 2000 and the Segi’s world standard population， the annual percentage change(APC) was estimated to analyze the trend of incidence and mortality， respectively. ［Results］ From 2013 to 2019， the incidence of lung cancer in Minhang District was 95.64/105， the ASRC and ASRW of incidence were 43.79/105 and 42.95/105， respectively. The mortality was 56.30/105， and the ASRC and ASRW of mortality were 21.04/105 and 20.93/105， respectively. There was no significant change in the incidence， ASRC and ASRW of lung cancer among the whole population and the male population from 2013 to 2019(P>0.05). The trend of incidence， ASRC incidence and ASRW incidence of female were increasing significantly， and the APC were 10.30%， 13.77% and 12.64%， respectively(P<0.05). The trend of mortality， ASRC mortality and ASRW mortality of male， female and the whole population were decreasing， and except for the ASRC mortality of male， the difference were statistically significant(P<0.05). The incidence and mortality of male were higher than those of female， and both increased with age， with differences were statistically significant(P<0.05). The total population incidence peaked in the age group of 80~84 years old and the peak mortality rate was in the age group of 85+ years old. In addition， from 2013 to 2019， the proportion of early stage of lung cancer increased from 10.44% to 16.98%. ［Conclusion］ From 2013 to 2019， there was no significant change in lung cancer incidence， ASRC and ASRW in Minhang District of Shanghai； while the mortality， ASRC and ASRW of mortality showed an downward trend. Lung cancer mainly occurr in male and the elderly， but the incidences of lung cancer in female and the young population are rising rapidly. The rate of early stage of lung cancer diagnosis is rising but still low， which needs to be paid attention to and actively explored.