| 六味参苓颗粒的质量标准研究 |
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| 引用本文： | 雷宁,王玲,孙健姿,吴诚,刘丽宏.六味参苓颗粒的质量标准研究[J].中国药房,2012(35):3328-3330. |
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| 作者姓名： | 雷宁 王玲 孙健姿 吴诚 刘丽宏 |
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| 作者单位： | 解放军第二炮兵总医院药学部,北京100088 |
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| 摘 要： | 目的:建立六味参苓颗粒的质量控制方法。方法:采用薄层色谱(TLC)法对处方中西洋参、黄芪、麦冬、茯苓、枳壳进行定性鉴别;采用高效液相色谱法测定西洋参中人参皂苷Rb1的含量。结果:TLC专属性强,阴性对照无干扰;人参皂苷Rb1的浓度在26.4～792.0μg·mL-1范围内与峰面积积分值呈良好的线性关系(r=0.9997),方法平均回收率为98.35%,RSD=2.09%(n=6)。结论:所建方法简便、可行,可用于六味参苓颗粒的质量控制。
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| 关 键 词： | 六味参苓颗粒 薄层色谱法 高效液相色谱法 人参皂苷Rb1 |
Study on Quality Standard of Liuwei Shenling Granules |
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| LEI Ning,WANG Ling,SUN Jian-zi,WU Cheng,LIU Li-hong.Study on Quality Standard of Liuwei Shenling Granules[J].China Pharmacy,2012(35):3328-3330. |
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| Authors: | LEI Ning WANG Ling SUN Jian-zi WU Cheng LIU Li-hong |
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| Institution: | (Dept. of Pharmacy, Second Artillery Forces Gen- eral Hospital of PLA, Beijing 100088, China) |
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| Abstract: | OBJECTIVE： To establish the quality control of Liuwei shenling granules. METHODS： Panax quinquefolium, As- tragali Radix, Ophiopogon japonicus, Poria cocos and Citrus aurantium were identified by TLC. The content of ginsenoside Rb1 in Panacis Quinquefolii Radix was determined by HPLC. RESULTS： The TLC identification method exhibited good specificities with- out interference form negative samples. The linear range of ginsenoside Rbl was 26.4-792.0 μg. mL^-1（r= 0.999 7） and the aver- age recovery was 98.35% （RSD=2.09% ,n=6）. CONCLUSION： The established standard is simple, feasible and suitable for the quality control of Liuwei shenling granules. |
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| Keywords: | Liuwei shenling granules TLC HPLC Ginsenoside R b1 |
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