尤瑞克林治疗血管性痴呆的临床观察

目的:观察尤瑞克林治疗血管性痴呆的临床效果。方法:将76名血管性痴呆患者随机均分为治疗组与对照组,治疗组给予尤瑞克林注射液治疗,对照组给予银杏叶注射液治疗,2组疗程均为14d。2组分别于治疗前、后检测简易智能状态测量表(MMSE)、日常生活能力评定量表(ADL)评分及血液流变学指标。结果:治疗组患者MMSE、ADL评分及血液流变学指标改善情况显著优于治疗前及对照组(P<0.05)。2组均未见明显不良反应发生。结论:尤瑞克林治疗血管性痴呆具有一定的治疗作用,疗效优于银杏叶注射液。

Efficacy Observation of Urinary Kallidinogenase in the Treatment of Vascular Dementia

OBJECTIVE： To investigate the effect of urinary kallidinogenase in the treatment of vascular dementia （VD）. METHODS： 76 cases of VD were randomized into therapy group and control group. Therapy group was treated with urinary kallidi- nogenase injection, and control group was treated with Ginkgo leaf injection for 14 days. The changes of MMSE and ADL score and hemorheology indexes were observed before and after treatment. RESULTS： The score of MMSE and ADL and hemorheology indexes in therapy group were significantly improved, compared with control group （P〈0.05）. No obvious adverse drug reaction was found. CONCLUSION： Urinary kallidinogenase has some therapeutic effect on VD, and the efficacy is better than Ginkgo leaf injection.