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肝移植后曲霉菌感染的危险因素分析
引用本文:钟林,彭志海,周新,韩伟,周晓敏,蔡逸婷.肝移植后曲霉菌感染的危险因素分析[J].中华医院感染学杂志,2007,17(3):278-280.
作者姓名:钟林  彭志海  周新  韩伟  周晓敏  蔡逸婷
作者单位:上海交通大学附属第一人民医院,上海市器官移植研究中心,上海,200080
摘    要:目的归纳分析肝移植后曲霉菌感染的高危因素。方法通过Logistic回归分析276例肝移植后受体曲霉菌感染的危险因素。结果移植后血透、粒细胞减少、机械通气时间过长、胆红素>20mg/dl和再移植是曲霉菌感染独立的预测因素。结论对高危受体及早预防治疗,有助于降低曲霉菌感染的发生率和死亡率。

关 键 词:肝移植  危险因素  侵袭性曲霉病
文章编号:1005-4529(2007)03-0278-03
收稿时间:2006-04-07
修稿时间:2006-06-15

Risk Factors of Invasive Aspergillosis after Liver Transplantation
ZHONG Lin,PENG Zhi-hai,ZHOU Xin,HAN Wei,ZHOU Xiao-min,CAI Yi-ting.Risk Factors of Invasive Aspergillosis after Liver Transplantation[J].Chinese Journal of Nosocomiology,2007,17(3):278-280.
Authors:ZHONG Lin  PENG Zhi-hai  ZHOU Xin  HAN Wei  ZHOU Xiao-min  CAI Yi-ting
Abstract:OBJECTIVE To identify risk factors for invasive aspergillosis(IA) in 276 liver transplant recipients.METHODS The risk factors have analyzed for IA in 276 liver transplant recipients with Logistic regression models.RESULTS Our results indicated that the independent risk factors for IA after liver transplantation were: hemodialysis after liver transplantation,granulocytopenia,prolonged days on mechanical ventilation,high bilirubin level,and retransplantation.CONCLUSIONS A confirmed postive test result should deserve a pre-emptive antifungal therapy in suspected recipient to reduce morbidity and mortality.
Keywords:Liver transplantation  Risk factors  Invasive aspergillosis
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