70岁以上首次和再发缺血性脑梗死颈动脉斑块及其相关临床参数对比研究

目的：研究70岁以上缺血性再发脑梗死患者颈部血管超声检查的变化规律。方法：采用随机、平行对照的方法,将既往已发脑梗死患者分为脑梗死再发组和非再发组,观察研究两组患者一般情况、合并疾病与颈动脉斑块变化特点,探讨脑梗死再发的原因。结果：两组患者在体型、饮酒、合并冠心病与心电图变化方面无明显差异,而在吸烟、合并高血压、糖尿病、高脂血症及高尿酸血症方面存在明显差异（P〈0.05）,颈部血管检查方面,两组患者在颈部血管狭窄方面,并无明显差异,而在颈动脉内膜中层厚度（IMT）、斑块性质与数量方面存在明显差异（P〈0.05）。结论：70岁以上缺血性脑梗死患者再发的原因是多方面的,除了与吸烟、高血压、高脂血、高尿酸和糖尿病等相关因素外,与颈动脉斑块有重要关系。提出在脑卒中二级预防中,应当进行常规颈部血管检查,对于有颈动脉斑块尤其是混合性斑块及非单一斑块者,应当重点监控,强化预防。

Over 70 Years Old the First Time and Recurrent Ischemic Stroke Carotid Artery Plaque and Its Related Clinical Parameters Comparative Study

Objective：To study over 70 years old with ischemic stroke in patients with recurrent cervical vascular ultrasound examination were studied.Methods：According to randomized,parallel-controlled method,past has been divided into two cerebral infarction in patients with cerebral infarction recurrence group and non-recurrence group,the general condition were observed in patients with combined changes in disease and carotid artery plaque characteristics of the brain infarction recurrence reasons.Results：Two patients size,alcohol consumption,coronary heart disease and no significant difference in changes in the electrocardiogram,while in the smoking,hypertension,diabetes,hyperlipidemia and hyperuricemia there significant differences （P〈0.05）,neck vascular screening,the two groups of patients with vascular stenosis in the neck area,there is no significant difference,while in the carotid artery intima-media thickness （IMT）,plaque there is the nature and quantity of significant differences （P〈0.05）.Conclusion：70 years old patients with ischemic stroke recurrence are many reasons,in addition to smoking,hypertension,hyperlipidemia,high uric acid and diabetes-related factors,and carotid artery plaque have important relations.Proposed secondary prevention of stroke,should be routine and neck vascular screening,for a carotid artery plaque,especially mixed plaques and non-single-plaque persons,should focus on monitoring and strengthening of prevention.