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糖尿病肾病中医体质易感性与基因多态性探析
引用本文:牟新,赵进喜,刘文洪,周旦阳,刘颖慧,胡永宾,马国玲,寿成珉,陈家炜. 糖尿病肾病中医体质易感性与基因多态性探析[J]. 中医药学刊, 2010, 0(6): 1181-1183
作者姓名:牟新  赵进喜  刘文洪  周旦阳  刘颖慧  胡永宾  马国玲  寿成珉  陈家炜
作者单位:[1]杭州市红十字会医院内分泌科,浙江杭州310003 [2]北京中医药大学东直门医院,北京100700 [3]浙江中医药大学,浙江杭州310053
基金项目:国家自然科学基金资助项目(30801467); 浙江省自然科学基金资助项目(Y2080683)
摘    要:提出在体质在糖尿病肾病的发生发展过程中的重要地位,阐述了体质形成的原因,不同体质2型糖尿病患者其糖尿病肾病发病率存在差异性,不同体质糖尿病肾病患者在存在基因多态性,建立具有创新性的糖尿病肾病中医病因学理论,促进中医学术进步,并为糖尿病肾病早期干预的可行性,为辨体质、辨病、辨证"三位一体"的糖尿病肾病辨证模式的建立奠定坚实的研究基础。

关 键 词:糖尿病肾病  体质  基因多态性

Association of Physiquein Chinese Medicine Susceptibility to Diabetic Nephropathy and Genetic Polymorphism
MU Xin,ZHAO Jin-xi,LIU Wen-hong,ZHOU Dan-yang,LIU Ying-hui,HU Yong-bin,MA Guo-ling,SHOU Cheng-min,CHEN Jia-wei. Association of Physiquein Chinese Medicine Susceptibility to Diabetic Nephropathy and Genetic Polymorphism[J]. Study Journal of Traditional Chinese Medicine, 2010, 0(6): 1181-1183
Authors:MU Xin  ZHAO Jin-xi  LIU Wen-hong  ZHOU Dan-yang  LIU Ying-hui  HU Yong-bin  MA Guo-ling  SHOU Cheng-min  CHEN Jia-wei
Affiliation:1.Hangzhou Red Cross Hospital,Hangzhou 310003,Zhejiang,China;2. Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;3.Zhejiang University of Chinese Medicine,Hangzhou 310053,Zhejiang,China)
Abstract:It expounded the important position of physique in etiology and process of diabetic nephropathy(DN),investigated essence and application of physique in DN control,revealed that the different morbidity in DN with different physique in diabetes,and different physique in DN will apperence genetic polymorphism.Also it expounded the significance of diagnosis of DN in TCM theory and clinical therapy,then to establish the originality TCM etiology theory. At last it expounded the trinity of physique differentiation and syndrome differentiation in treating DN.
Keywords:diabetic nephropathy  physique  genetic polymorphism
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