艾灸三阴交穴缓解兔子宫痉挛的实验研究 |
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引用本文: | 王超,常小荣,严洁,刘佳玟. 艾灸三阴交穴缓解兔子宫痉挛的实验研究[J]. 中医药学刊, 2010, 0(5): 967-969 |
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作者姓名: | 王超 常小荣 严洁 刘佳玟 |
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作者单位: | 湖南中医药大学针灸经络研究所,湖南长沙410007 |
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基金项目: | 国家重点基础研究发展计划(973计划资助项目)(2009CB522904) |
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摘 要: | 目的:探讨艾灸不同穴位对雌性家兔未孕的子宫痉挛性收缩频率、幅度和血清钙离子(Ca^2+)、钾离子(K^+)及血浆内皮素(ET)含量的影响,分析不同穴位对子宫肌痉挛的缓解作用及其部分机制。方法:通过注射缩宫素造成子宫痉挛模型,分别空白组、模型组、艾灸三阴交、足三里、非经非穴点。结果:艾灸三阴交穴组子宫肌活动参数恢复至注射药物缩宫素(OT)前水平,而其余各组未恢复,且三阴交穴组Ca^2+水平明显高于其它两组,而K^+明显低于其余两组,各组对NO、ET含量变化均未见统计学差异。结论:三阴交穴对子宫肌痉挛的缓解作用有一定的特异性,艾灸三阴交穴缓解痛经的作用机理是通过调节血清钙-钾平衡而达到的。
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关 键 词: | 艾灸 三阴交 子宫肌活动 钙离子 钾离子 兔 |
Experimental Research on the Mitigation Effect of Moxibustion at Sanyinjiao Points on Uterine-spasm of the Rabbit |
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Affiliation: | WANG Chao,CHANG Xiao-rong,YAN Jie,LIU Jia-wen(Institute of Acupuncture and Meridian,Hunan University of Chinese Medicine,Changsha 410007,Hunan,China) |
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Abstract: | Objective:To observe the effect of moxibustion at different acupoints on frequency and amplitude of hysterospasm,content of Ca^2+ and K^+ in serum and ET in plasma in female Nonfertile rabbits,and to probe the mechanism.Methods:30 rabbits were randomly divided into 5 groups:blank group,model group,moxibustion at sanyinjiao points group;moxibustion at zusanli points group;moxibustion at non-acupoints.The animal model of uterine spasm was established by oxytocin injection.Results:After moxibustion at sanyinjiao point,the parameters of uterine movements reached the values before oxytocin injection.Compared with the other two moxibustion groups,the content of Ca^2+ was significantly higher,while the content of K^+ was significantly lower in sanyinjiao point group.The content of NO and ET had no significant difference among the groups.Conclusion:Moxibustion at sanyinjiao point could relieve uterine spasm.The mechanism of anti-spastic effect of moxibustion at sanyinjiao points is to regulate calcium-potassium balance in serum. |
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Keywords: | moxibustion sanyinjiao myometrium activity Calcium in blood serum K in blood serum rabbit |
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