| 不同频率电针对切卵大鼠松质骨空间结构的影响s |
| |
| 引用本文： | 金肖青,詹红生,石巧娟,陈益丹.不同频率电针对切卵大鼠松质骨空间结构的影响s[J].中医药学刊,2010(4):817-819. |
| |
| 作者姓名： | 金肖青 詹红生 石巧娟 陈益丹 |
| |
| 作者单位： | [1]浙江医院,浙江杭州310013 [2]上海中医药大学骨伤研究所,上海201203 [3]浙江省医学科学院动物实验中心,浙江杭州310012 |
| |
| 基金项目： | 基金项目：浙江省自然科学基金资助项目（Y206946） |
| |
| 摘 要： | 目的：观察电针不同脉冲频率对切卵大鼠松质骨结构的影响,探讨电针治疗原发性骨质疏松模型大鼠的最佳刺激参数。方法：采用电针2Hz、100Hz、2/100Hz不同频率对去卵巢骨质疏松大鼠进行治疗,以倍美力灌胃作为对照组,观察Micro-CT下大鼠松质骨空间结构参数以及血清E2、PICP、ICTP的变化。结果：电针组能不同程度提高模型大鼠骨小梁数目、厚度、骨体积分数和血清E2、PICP含量,减小骨小梁间隙、骨表面积体积比,降低血清ICTP水平;其中以100Hz频率电针组疗效更为明显。结论：电针对骨质疏松大鼠骨小梁空间结构具有一定的保护作用,并且这种保护作用以100Hz频率电针刺激更为明显。
|
| 关 键 词： | 电针 不同频率 切卵大鼠 骨空间结构 |
Effects of Electro-Acupuncture with Different Frequency on Space Structures of Cancellous Bone in the Ovariectomized Rat Model |
| |
| JIN Xiao-qing,ZHAN Hong-sheng,SHI Qiao-juan,CHEN Yi-dan.Effects of Electro-Acupuncture with Different Frequency on Space Structures of Cancellous Bone in the Ovariectomized Rat Model[J].Study Journal of Traditional Chinese Medicine,2010(4):817-819. |
| |
| Authors: | JIN Xiao-qing ZHAN Hong-sheng SHI Qiao-juan CHEN Yi-dan |
| |
| Institution: | 1. Zhejiang Hospital, Hangzhou 310013, Zhejiang, China; 2. Department of Orthopedics and Traumatology,Tradition Chinese Medicine Academy of Shanghai, Shanghai 201203, China; 3. Center of Experiment Animal of Zhejiang Academy of Medicine, Hangzhou 310012,Zhejiang, China) |
| |
| Abstract: | Objective： To observe the effects of electro-acupuncture with different frequency on space structures of cancellous bone in the ovariectomized rat model, and seek the optimal parameter of electro-acupuncture in treating osteoporosis in ovariectomized rat model. Methods： To treat The ovariectomized rats model with osteoporosis , electro-acupuncture groups were treatedwith 2Hz,100Hz and 2/100 Hz three different frequencies, the control group received gastric perfusion of Premarin , and investigate the parameters of cancellous bone space structures with Micro-CT, and the changes of serum estradiol （E2）, carboxyterminal propeptide of type I procollagen（PICP）,carboxyterminal telopeptide of type I collagen（ICTP）.Results：Electro-acupuncture groups could significantly enhance trabecular number（Tb N）, trabecular thickness （Tb.Th）,bone volume fraction（BV/TV）and serum E2, PICP ,while trabecular spacing （Tb.Sp）, bone surface/bone volume （BS/BV） and serumICTP were reduced significantly in the ovariectomized rat model, therapeutic effect especially better of 100Hz frequency. Conclusion： Electro-acupuncture has protective effect on cancellous bone space structures in the ovariectomized rat model, and 100Hz maybe the best stimulate parameter. |
| |
| Keywords: | electro-acupuncture different frequency ovariectomized rat bone space structures |
| 本文献已被 维普 等数据库收录！ |
|
