小儿纵隔肿瘤的CT影像和临床分析

目的 研究小儿从隔肿瘤的ＣＴ诊断特征和临床特点。方法 １５例小儿纵隔肿瘤、其中神经母细胞瘤５例，神经节细胞瘤３例，神经鞘瘤１例，胸腺瘤及畸胎瘤各２例，淋巴管瘤和内胚实瘤各１例。各地术前、化疗前行胸部ＣＴ平扫和增强扫描，３例神经线细胞瘤治疗前、后作尿ＶＭＡ测定和同步ＣＴ扫描。结果 畸胎瘤和胸腺瘤位于前纵隔，神经源性肿瘤和内胚窦瘤发生于后纵隔。神经母细胞瘤瘤呈呈浸润性生长、钙化、破坏及骨质破坏多见，胸

CT Scan and Clinical Evaluation of Mediastinal Neoplasms in Children

Objective To study clinical presentations and CT features of mediastinal tumours in children. Methods Fifteen children with mediastinal tumours were studied retrospectively. There were neuroblastoma (NS, 5), ganglioneuroma (3), Schwannoma(1), thymoma (2), teratoma (2), lymphangioma (1) and endodermal sinus tumour (EDST 1). CT scans with and without contrast were performed before and after operations or chemotherapy. Results Thymomas and teratomas tended to be located in the anterior mediastinum, whereas neurogenic tumours and EDST predisposed to the posterior mediastinum. Thymoma had capsules. Fat and calcification were commonly observed in the teratoma. Infiltration, bony destruction, necrosis and calcification were characteristic of NB (the urine VMA of three patients with NB failed to respond to chemotherapy despite shrinkage in size). Conclusions CT scans are accurate in the diagnosis and follow up of pediatric mediastinal tumours. CT scan is superior to urinal VMA levels in assessing tumour response to chemotherapy.