| HPLC法测定药物含量的不确定度分析 |
| |
| 引用本文： | 孙莉. HPLC法测定药物含量的不确定度分析[J]. 安徽医药, 2010, 14(7): 776-777. DOI: 10.3969/j.issn.1009-6469.2010.07.015 |
| |
| 作者姓名： | 孙莉 |
| |
| 作者单位： | 安徽省芜湖市食品药品检验所,安徽,芜湖,241001 |
| |
| 摘 要： | 目的建立替硝唑胶囊含量测定中不确定度的分析方法。方法采用HPLC法测定含量的数学模型,确定影响不确定度的因素并对各个不确定度因素进行评估。结果替硝唑胶囊含量测定的合成不确定度为0.9%;扩展不确定度为1.8%;测定结果为（99.1±1.8）%。结论本方法可用于HPLC法测定该制剂含量的不确定度分析。
|
| 关 键 词： | 不确定度 HPLC法 含量测定 替硝唑胶囊 |
Uncertainty of the determination of Tinidazole Capsules |
| |
| SUN Li. Uncertainty of the determination of Tinidazole Capsules[J]. Anhui Medical and Pharmaceutical Journal, 2010, 14(7): 776-777. DOI: 10.3969/j.issn.1009-6469.2010.07.015 |
| |
| Authors: | SUN Li |
| |
| Affiliation: | SUN Li(Wuhu Institute for Food , Drug Control,Wuhu,Ahnhui 241001) |
| |
| Abstract: | Aim To establish a method for uncertainty analysis in HPLC determination.Method The calculation formula of uncertainty was deduced in the procedure of determining the content in capsules.Results The combined uncertainty was 0.9 %,the extended uncertainty was 1.8%,and the determined content were 99.1%±1.8%.Conclusion The mathematic model of uncertainty measurement established in this paper is reasonable and reliable. |
| |
| Keywords: | uncertainty HPLC content tinidazole capsules |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
