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Inactivating mutations of tumor suppressor genes KLOTHO and DTWD1 in colorectal cancers
Affiliation:1. Division of Pathology, Cancer Institute of Japanese Foundation for Cancer Research, Tokyo, Japan;2. Department of Comprehensive Pathology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan;3. Department of Pathology, Cancer Center, Mittaphab Hospital, Vientiane, Lao People''s Democratic Republic;4. Department of Pathology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan;5. Breast Oncology Center, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan;6. Diagnostic Imaging Center, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan;7. Department of Pathology, Kawakita General Hospital, Tokyo, Japan;8. Pathology Project for Molecular Targets, Cancer Institute of Japanese Foundation for Cancer Research, Tokyo, Japan;1. Department of Pathology, Hengxian People’s Hospital, 141 Jiaoyu Road, Hengxian County of Nanning 530300, Guangxi Zhuang Autonomous Region, People’s Republic of China;2. Department of Pathology, First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, People’s Republic of China;3. Department of Radiotherapy, First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, People’s Republic of China;1. Department of Biochemistry, Provincial Key Laboratory of Biological Macro-molecules Research, Wannan Medical College, Wuhu, Anhui, 241002, China;2. Department of Clinical Teaching, The First Affiliated Hospital of Wannan Medical College, Wuhu, Anhui, 241002, China;3. First Clinical College, Southern Medical University, Guangzhou, Guangdong, 510000, China;1. Department of Pathology, The First Affiliated Hospital of Xinjiang Medical University, No. 137 Liyushan Southern Road, Urumqi, the Xinjiang Uygur Autonomous Region of China, 830054, PR China;2. Xinjiang Medical University, No. 393 Xinyi Road, Urumqi, the Xinjiang Uygur Autonomous Region of China, 830011, PR China;1. Morphology Experiment & Training Center, School of Preclinical Medicine, Wannan Medical College, Wuhu 241002, Anhui, China;2. Department of Neurosurgery, Yijishan Hospital of Wannan Medical College, No. 2 Zheshan Road, Wuhu 241001, Anhui, China;1. Department of General Surgery and Transplantation “P. Stefanini”, Sapienza University of Rome, Italy;2. Department of General Surgery and Transplantation, San Salvatore Hospital, L''Aquila University, L''Aquila, Italy
Abstract:
Keywords:Mutation  Tumor suppressor genes  Microsatellite instability
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