2005-2007年兰州市恶性肿瘤发病状况分析

目的 探讨兰州市人群恶性肿瘤发病状况及趋势,分析癌谱结构,确定重点防治人群.方法 收集兰州市5区2005年1月1日～2007年12月31日常住人口中所有新发和死亡的恶性肿瘤病例和中枢神经系统良性肿瘤,统计分析发病率及其相关指标.结果 2005 -2007年兰州市5区登记报告恶性肿瘤10 594例,恶性肿瘤发病率为204.39/10万,其中,男性为229.29/10万,女性为177.52/10万；中国人口标化发病率为164.98/10万,男性为191.51/10万,女性为138.51/10万；男性恶性肿瘤发病率高出女性29.16％.发病率居前10位的肿瘤,男性依次是肺癌、胃癌、肝癌、结直肠癌、食管癌、膀胱癌、胰腺癌、肾癌、前列腺癌和淋巴瘤,占全部恶性肿瘤的82.12％；女性依次是乳腺癌、肺癌、宫颈癌、胃癌、结直肠癌、胆囊癌、肝癌、卵巢癌、子宫体癌和脑及神经系统肿瘤,占全部恶性肿瘤的75.57％.5区中,城关区恶性肿瘤病例数最多,占兰州市的50.39％;西固区恶性肿瘤发病率最高,为225.03/10万.3年间,兰州市恶性肿瘤发病率呈上升趋势(x2趋势=2.84,P=0.005).男性发病率上升趋势显著(x2趋势=2.37,P=0.018).结论 兰州市居民恶性肿瘤以肺癌、胃癌、结直肠癌和肝癌及女性乳腺癌和宫颈癌为主,严重威胁居民健康.西固区是重点防治地区,男性和老年人群是重点防治对象.

Incidence of malignant tumors in Lanzhou City, 2005 - 2007

Objective To explore the incidence,trend and the spectrum of tumors in Lanzhou City,2005-2007,and identify the high-risk population in the certain area.Methods Data on morbidity and mortality of malignant tumors and central nervous system benign tumors among the resident population of Lanzhou City during 2005 and 2007 was collected by using the methods of cancer registration reports.The number of new cancer cases,crude incidence and other indexes were calculated.Results Between January 1,2005 and December 31,2007,a total of 10 594 cases of malignant tumors were reported in Lanzhou City.The overall incidence of malignant tumors was 204.39/100 000（229.29/100 000 and 177.52/100 000 for male and female,respectively）.Age-adjusted incidence of malignant tumors by Chinese standard population was 164.98/100 000,it was 29.16% higher in male（191.51/100 000） than in female（138.51/100 000）.The ten most common cancers,in decreasing order of incidence,were lung cancer,stomach cancer,liver cancer,colorectal cancer,esophageal cancer,bladder cancer,pancreatic cancer,kidney cancer,prostate cancer and lymphoma in male,which accounted for 82.12% of the total incidence of malignant tumors in male;and breast cancer,lung cancer,cervical cancer,stomach cancer,colorectal cancer,gallbladder cancer,liver cancer,ovarian cancer,uterine body cancer and brain and nervous system benign tumors in female,which accounted for 75.57% of the total incidence of malignant tumors in female.The case number of the malignant tumors was most in Chengguan District,which accounted for 50.39% of the overall number in the whole city.The incidence of the malignant tumors was the highest in Xigu District（225.03/100 000）.The incidence of malignant tumors in Lanzhou was increasing during 2005 and 2007（χ2trend=2.84,P=0.005）.The incidence of the malignant tumors was increased significantly in male（χ2trend=2.37,P=0.018）.Conclusions Malignant tumor is a serious problem of the health in Lanzhou City.It should be paid more attention to lung cancer,stomach cancer,colorectal cancer,liver cancer and female breast cancer and cervical cancer.Xigu District is the high-risk area of malignant tumors.Males and the elders are the high-risk population.