Histamine H1 receptor antagonist blocks histamine-induced proinflammatory cytokine production through inhibition of Ca2+-dependent protein kinase C, Raf/MEK/ERK and IKK/I kappa B/NF-kappa B signal cascades |
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| Authors: | Matsubara Masahiro Tamura Tadafumi Ohmori Kenji Hasegawa Kazuhide |
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| Institution: | Department of Pharmacology and Molecular Biology, Pharmaceutical Research Center, Kyowa Hakko Kogyo Co. Ltd., Shizuoka 411-8731, Japan. masahiro.matsubara@kyowa.co.jp |
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