原发性脑淋巴瘤MRI表现及其病理基础

目的探讨原发性脑淋巴瘤的MRI表现及病理基础，提高对脑原发性淋巴瘤的认识。方法回顾分析2010年1月-2012年5月28例确诊为脑原发性淋巴瘤的MRJ影像特征及临床病理资料。结果28例患者，共发现36个病灶，幕上病灶34个，幕下病灶2个；MRI平扫；32个病灶在T1WI、T2WI肿瘤实质表现为等信号；4个病灶内出现液化坏死（其中1个病灶呈明显囊变），信号不均。MRI增强扫描：35个肿瘤病灶实质部分均匀强化，1个病灶呈环形强化。病理类型均为弥漫性大B细胞非霍奇金淋巴瘤。结论原发性脑淋巴瘤具有较典型的MRj影像特征，可在术前明确诊断。

Magnetic Resonance Imaging Features and Pathologic Basis of Primary Central Nervous System Lymphoma

Objective To analyze the magnetic resonance imaging （MRI） features of primary central nervous system lymphoma （PCNSL）, for improving the recognition of this disease. Methods We retrospectively analyzed the MRI features and the clinical pathological data of 28 patients with PCNSL treated in our hospital from January 2010 to May 2012. Results In the 28 PCNSL patients, 36 lesions were detected by MRI, including 29 located in supratentorial site and 7 found in infratentorial site. MRI plain scan showed that 32 lesions displayed isointensity on T1WI and T2WI, except that four lesions had obvious necrosis or hemorrhage. All lesions displayed obvious homogeneous enhancement on MRI enhanced scan. Postoperative pathological findings showed that all lesions had diffused large B-cell lymphoma. Conclusions PCNSL has typical MRI features. If doctors are familiar with the MRI features of PCNSL, an accurate diagnosis can be made before surgery.