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某院老年患者革兰阴性杆菌耐药情况分析
引用本文:张金安,郭均平,陈红,夏迪.某院老年患者革兰阴性杆菌耐药情况分析[J].中国药师,2011,14(12):1772-1773.
作者姓名:张金安  郭均平  陈红  夏迪
作者单位:湖北武警总队医院药剂科 武汉430061
摘    要:目的:分析我院老年住院患者临床标本细菌培养及对常用的抗菌药耐药情况,为临床合理使用抗菌药及减少细菌耐药的发生提供参考。方法:对我院2009年6月~2011年3月年龄为65~87岁老年住院患者511例临床标本培养分离出167株细菌进行鉴定及药敏试验。结果:常见病原菌以G~-杆菌为主,占70.66%;其次是G~+菌,占29.34%;细菌对亚胺培南普遍敏感,敏感率为97.5%。结论:老年患者主要为G~-杆菌感染,但G~+菌感染率逐年上升;耐药菌株检出率高,应引起足够的重视;同时医护人员要加强预防耐药菌感染应对措施,减少细菌耐药情况的发生。

关 键 词:老年患者  革兰阴性杆菌  抗菌药  耐药  合理用药

Analysis of Drug Resistance to Gram-negative Bacteria in Senile Patients
Zhang Jinan , Guo Junping , Chen Hong , Xia Di.Analysis of Drug Resistance to Gram-negative Bacteria in Senile Patients[J].China Pharmacist,2011,14(12):1772-1773.
Authors:Zhang Jinan  Guo Junping  Chen Hong  Xia Di
Institution:( Department of Pharmacy, Hubei Provincial Hospital of Armed Police Force, Wuhan 430061 )
Abstract:Objective: To analyze the culture and antibiotics resistance of the clinical bacteria from the secretion of senile inpatients to offer the information for rational use of antibiotics and reduce the drug resistance. Method: 167 bacteria strains from the senile inpatients with the age between 65 and 87 from June ,2009 to March ,2011 were selected for the identification and drug sensitivity test. Result: The major pathogenic bacteria were G- bacteria with the percentage of 70. 66% followed by the G- bacteria with the percentage 22.03%. They were generally sensitive to imipenem with the sensitivity ratio of 97. 5%. Conclusion: The major pathogenic bacteria in senile patients are G-bacteria with the increasing inflammation of G - bacteria year by year. The high detection rate of the drug resistance bacteria should be paid more attention. Actions also should be taken by the medical staff to avoid the bacteria drug resistance.
Keywords:Senile patients  G- bacteria  Antibiotics  Drug resistance  Analysis
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