| IL-33/ST2信号通路在纤维化疾病中的作用 |
| |
| 引用本文： | 高巧艳,李明才,李燕,王亚清,高雪明,袁仙丽. IL-33/ST2信号通路在纤维化疾病中的作用[J]. 中国病理生理杂志, 2013, 29(9): 1712-1717. DOI: 10.3969/j.issn.1000-4718.2013.09.032 |
| |
| 作者姓名： | 高巧艳 李明才 李燕 王亚清 高雪明 袁仙丽 |
| |
| 作者单位： | 宁波大学医学院免疫学研究室，浙江 宁波 315211 |
| |
| 基金项目： | 国家自然科学基金资助项目(项目编号：81070034),浙江省自然科学基金资助项目(项目编号：LY13H090014)宁波市科技创新团队项目(项目编号：2011B82014)宁波市重点学科项目(项目编号：XKL11D2112,XKL11D2113)宁波大学研究生科研创新基金资助项目(项目编号：G12JA004) |
| |
| 摘 要： |
|
| 关 键 词： | 白细胞介素33 ST2蛋白 纤维化疾病 |
| 收稿时间： | 2013-03-21 |
Role of IL-33/ST2 signaling pathway in fibrosis diseases |
| |
| GAO Qiao-yan , LI Ming-cai , LI Yan , WANG Ya-qing , GAO Xue-ming , YUAN Xian-li. Role of IL-33/ST2 signaling pathway in fibrosis diseases[J]. Chinese Journal of Pathophysiology, 2013, 29(9): 1712-1717. DOI: 10.3969/j.issn.1000-4718.2013.09.032 |
| |
| Authors: | GAO Qiao-yan LI Ming-cai LI Yan WANG Ya-qing GAO Xue-ming YUAN Xian-li |
| |
| Affiliation: | Department of Immunology, Medical School of Ningbo University, Ningbo 315211, China. |
| |
| Abstract: | Interleukin (IL)-33 is a member of IL-1 family. It is identified as a functional ligand for ST2 which is an IL-1 receptor-like protein. IL-33/ST2 signaling is involved in T-cell-mediated immune responses. Increasing evidence indicates that IL-33 has different roles in different diseases. Recently, some studies have demonstrated that IL-33 may be related to the genesis and development of fibrosis diseases. We review current knowledge of the biological characteristics of IL-33 and the role of IL-33/ST2 signaling pathway in fibrosis diseases. |
| |
| Keywords: | Interleukin-33 ST2 protein Fibrosis diseases |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《中国病理生理杂志》浏览原始摘要信息 |
|
点击此处可从《中国病理生理杂志》下载免费的PDF全文 |
