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| 莪术油喷雾剂的研制及抗病毒作用的实验研究 | |
| 引用本文： | 黄亚东,项琪,姚崇舜,张奉学,张卉,李校堃. 莪术油喷雾剂的研制及抗病毒作用的实验研究[J]. 中药材, 2007, 30(3): 342-345 |
| 作者姓名： | 黄亚东 项琪 姚崇舜 张奉学 张卉 李校堃 |
| 作者单位： | 1. 暨南大学医药生物技术研究开发中心,广东广州,510632 2. 暨南大学生命与健康工程研究院,广东广州,510632 3. 温州医学院药学院,浙江温州,325035 4. 广州中医药大学,广东广州,510405 |
| 摘 要： | 目的:研制莪术油喷雾剂,并对其抗病毒作用进行实验研究。方法:对莪术油葡萄糖注射液进行剂型改革,确定莪术油喷雾剂的处方和制备工艺,用HPLC法测定莪术醇和=牛儿酮的含量,同时进行了莪术油喷雾剂体内外抗病毒实验。结果:制备的莪术油喷雾剂质量可控,对流感病毒,副流感病毒Ⅰ、Ⅲ,呼吸道合胞病毒,3、7型腺病毒有轻微抑抑制作用,对副流感Ⅱ型病毒有较强的抑制作用。结论:本莪术油喷雾剂制备简单易行,给药方便,具有一定的抗病毒作用。 |
| 关 键 词： | 莪术油 制备 抗病毒作用 |
| 文章编号： | 1001-4454(2007)03-0342-04 |
| 修稿时间： | 2006-09-25 |
Study on the Preparation of Zedoary Turmeric Oil Spray and Its Anti-virus Effects |
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| HUANG Ya-dong,XIANG Qi,YAO Chong-shun,ZHANG Feng-xue,ZHANG Hui,LI Xiao-kun. Study on the Preparation of Zedoary Turmeric Oil Spray and Its Anti-virus Effects[J]. Journal of Chinese medicinal materials, 2007, 30(3): 342-345 | |
| Authors: | HUANG Ya-dong XIANG Qi YAO Chong-shun ZHANG Feng-xue ZHANG Hui LI Xiao-kun |
| Affiliation: | Biopharmaceutical Research & Development Center of Jinan University, Guangzhou 510632, China. ydhuang2004@126.com |
| Abstract: | OBJECTIVE: To prepare the Zedoary Turmeric Oil spray and investigate its anti-virus effects. METHODS: According to the Zedoray Turmeric Oil and Glucose Injection, the new dosage of Zedoray Turmeric Oil spray was studied. Antiviral effects of the Zedoary Turmeric Oil spray in the respiratory tract were studied both in vivo and in vitro. RESULTS: The quality of the Zedoary Turmeric Oil spray was controlled. The influenza virus, parainfluenza Virus I, III, RS virus and AD virus 3,7 could be inhibited slightly, but the parainfluenza Virus II could be obviously inhibited by the Zedoary Turmeric Oil spray. CONCLUSION: The Zedoary Turmeric Oil spray's formula is simple, useful and safe. |
| Keywords: | Zedoary Turmeric Oil Preparation Anti-virus |
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