溃疡性结肠炎的临床特征分析

目的探讨溃疡性结肠炎（UC）的临床特征。方法对确诊的182例UC患者的临床症状、结肠镜、病理、实验室检查结果进行回顾性分析。结果182例UC患者临床表现以黏液脓血便（77．5％）、腹泻（45．1％）、腹痛（43．4％）为主；结肠镜示黏膜充血水肿、多发糜烂及溃疡形成多见；病变分布以直肠乙状结肠（30．2％）、左半结肠（23．1％）为主；临床分型以初发型（56．0％）、程度以轻度（56．0％）为主；活化部分凝血活酶时间（APTT）及凝血酶原时间（PT）各组间比较无统计学意义；纤维蛋白原（FIB）临床轻度组与重度组比较，差异有统计学意义（P〈0．05）。结论UC临床表现以轻中度多见，病变分布以直肠乙状结肠型最多见；轻度以直肠乙状结肠型为主，重度以全结肠型为主；轻度与重度之间FIB有差异。

Analysis of clinical characteristics of 182 patients with ulcerative colitis

Objective To analyze the clinical characteristics of the patients with ulcerative colitis.Mothods The 182 UC cases were analyzed retrospectively in terms of symptoms,laboratory test,endoscope manifestations and pathological results.Results The main clinical manifestations were bloody stool(77.5%),diarrhea(45.1%),and abdominal pain(43.4%).Under endoscope examination,mucosa congestion,erosion and ulcer were mainly found.The main sites of lesion were located at rectosigmoid(30.2%),left colon(23.1%),and rectum(...