服用抗精神病药物患者血压、心率的测量与观察

为了降低服用抗精神病药物患者体位性低血压的发生率，对62例精神分裂症患者在增药期间，取不同体位进行了血压和心率的测量。结果：平卧位的收缩压、舒张压、心率与直立位比较（经配对t检验）差异有非常显著性（P＜0．01）。直立位与平卧位相比，心率平均快41次／min，舒张压平均高1．1kPa，而收缩压平均低1．32kPa。其中有5例患者平卧位收缩压正常，而直立位时收缩压＜12kPa。作者提出：①给服用抗精神病药物患者测量血压、心率时，应分别取平卧和直立位进行测量，才能了解患者血压和心率的变化。②增药期间应采取直立位测量，对预防体位性低血压有重要意义。

Study on Measuring Blood Pressure and Heart Rate in Patients Taking Antipsychotics

the prevalence of orthatatic hpoension in patients taking antipsyhotics 62pchizophrencs' blood pressure and heart rate were measured at different peture. The data showed that thesystoic Prso,diastolic ponre and ha rate in supine ~tion wer statisticaIly different fm tfor atStanling position (P < 0. 0l ). In standing position the heart rate was 4l/min higher, the systolic pressure l. 32kPa lower and the diastoic pressure l. 2kPa higher than those in supine position. The systolic pressure of 5 cases were normal in supine position and under l2kPa in standing position,It is cocluded that the heart rateand blood pressure should be meased both in staning and supine position in petients taking antipsychotics, soas to prevet the onset of orthostatic hypotension.