特发性肺纤维化的CT征象分析及其临床意义

目的：探讨特发性肺纤维化（IPF）的cT表现特征及其临床意义。方法：回顾性分析25例IPF患者的CT表现及复习文献资料，总结其特征。结果：25例IPF患者的CT表现复杂多样，磨玻璃样高密度灶1例，网格状变25例，蜂窝状变22例，支气管及细支气管牵拉性扩张23例，界面征20例，胸膜下线16例，支气管血管束增粗12例，纵隔淋巴结肿大14例，胸膜增厚15例，肺动脉高压8例，肺大泡5例。病变以网格状、蜂窝状变为主，主要位于肺基底部及肺外围，且病变由肺尖到肺底逐渐增多，由肺外围到肺门侧逐渐减轻。结论：IPF的CT征象及其分布具有特征性，结合临床可作出明确诊断。

Analysis of CT Features in Idiopathic Pulmonary Fibrosis and Its Clinical Significance

Objective： To investigate the CT features of idiopathic pulmonary fibrosis （ IPF ） and its clinical significance. Method： The CT manifestations were analyzed retrospectively in 25 cases of IPF and the literatures were reviewed. Result： CT manifestations of 25 cases of IPF were complex. Ground-glass opacity was seen in 1 case, reticular pattern in 25 cases , honeycombing in 22 cases , bronchial and bronchioles tractional expansion in 23 cases , interface sign in 20 cases , subpleural line in 16 cases , bronchial blood vessel bundle enlargement in 12 cases , mediastinal lymph node enlargement in 14 cases , pleural thickening in 15 cases , pulmonary hypertension in 8 cases, and pulmonary bullae in 5 eases. Reticular pattern and honeycombing were mostly , predominantly distributed in the basal segments and the peripheral zone of the lung, and gradually increased from the apex to the base of the Dung , gradually reduced from the periphery to the pulmonary hilar. Conclusion： CT manifestations and predominant distribution of IPF are characteristic , a definite diagnosis can be. made by combining with the clinical.