地塞米松冲击疗法治疗成人原发免疫性血小板减少症的疗效观察 |
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引用本文: | 张付华,刘珍.地塞米松冲击疗法治疗成人原发免疫性血小板减少症的疗效观察[J].现代保健,2014(34):90-92. |
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作者姓名: | 张付华 刘珍 |
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作者单位: | 山东省东营市人民医院,山东东营257091 |
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摘 要: | 目的:观察地塞米松冲击疗法治疗成人原发免疫性血小板减少症(ITP)的临床疗效。方法:自2006年7月-2013年9月间笔者所在医院收治成人ITP患者38例,患者均给予胸腺肽α1联合大剂量维生素C治疗,其中19例同时应用4 d地塞米松冲击治疗,观察临床症状、血小板计数和不良反应。结果:胸腺肽α1+大剂量维生素C治疗组总有效率78.9%,平均起效时间(16.8±3.2)d;胸腺肽α1+大剂量维生素C联合地塞米松冲击治疗组总有效率84.2%,平均起效时间(6.7±2.7)d。两种治疗方案的不良反应均较轻微。结论:胸腺肽α1联合大剂量维生素C与冲击量地塞米松联合应用治疗成人ITP疗效较好,副作用少,可缩短起效时间。
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关 键 词: | 免疫性血小板减少症 胸腺肽α1 维生素C 地塞米松 |
The Efficacy Observation of Dexamethasone Impact Therapy in the Treatment of Immune Thrombocytopenic Purpura |
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Authors: | ZHANG Fu-hua LIU Zhen |
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Institution: | (The People's Hospital of Dongying City, Dongying 257091, China) |
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Abstract: | Objective:To observe the curative effect of Dexamethasone impact therapy to the immune thrombocytopenic purpura(ITP).Method:38 ITP patients were all given thymosin alpha 1(Tα1) combined highdose vitamin C,among them 19 patients were companied with flushing dose dexamethasone during the first 4 medicative days.The clinic syndrome,platelet counts and side effects were observed.Result:The total effective rate in Tα1 combined high-dose vitamin C therapy group reached 78.9%,the average onset time were(16.8±3.2)d;the total effective rate in Tα1 combined high-dose vitamin C and flushing dose dexamethasone therapy group was 84.2%, the average onset time were(6.7±2.7)d.The side effects of the two groups were slight.Conclusion:Tα1 combined highdose vitamin C and flushing dose dexamethasone has good curative effect and fewer side effects on adult ITP; it can also act fsatly. |
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Keywords: | Immune thrombocytopenia Thymosin alpha 1 Vitamin C Dexamethasone |
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