老年慢性阻塞性肺疾病合并肺部感染的相关性因素分析

目的：探讨老年慢性阻塞性肺疾病（COPD）合并肺部感染的影响因素。方法：回顾性分析本院169例老年COPD患者的临床资料,采用单因素和多因素Logistic回归分析COPD合并肺部感染的影响因素。结果：肺部感染并发症发生率36.09%（61/169）;性别、合并症、住院时间、吸烟、抗生素滥用、侵入性操作、糖皮质激素应用、呼吸机辅助呼吸、卧床、近期感染和营养不良程度不同等在老年COPD合并肺部感染中的差异均有统计学意义（P〈0.05）;其中抗生素滥用史、低蛋白血症和糖皮质激素应用史等是COPD并发肺部感染的独立危险因素（P〈0.05）。结论：老年COPD合并肺部感染与滥用抗生素、低蛋白血症、呼吸机辅助呼吸和糖皮质激素等因素相关。

Correlative Factors Analysis of Elderly Chronic Obstructive Pulmonary Disease Combine with Pulmonary Infection

Objective： To investigate the correlative factors of elderly chronic obstructive pulmonary disease（COPD） combine with pulmonary infection.Method： The clinical data of 169 elderly patients with COPD were retrospective analyzed in our hospital, and used univariate and multivariate Logistic regression analysis on influencing factors of COPD combine with pulmonary infection.Result：COPD infection rate was 36.09%（61/169）, the single factor analysis finds, the difference of gender, comorbidity,hospitalization time, smoking, antibiotics overuse, invasive operation, glucocorticoid use, ventilator assisted breathing, bed, recent infection and malnutrition of the patients had significantly differences（P〈0.05）. Multi factor Logistic regression analysis showed, the antibiotics overuse history, hypoproteinemia and glucocorticoid application were independent risk factors of elderly patients with COPD combine pulmonary infection（P〈0.05）.Conclusion： Elderly patients with chronic obstructive pulmonary disease combine with pulmonary infection is corrected with the abuse of antibiotics, hypoproteinemia, ventilator assisted breathing and glucocorticoid and other relevant factors.