| 纳米载体应用于透皮给药系统的研究进展 |
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| 引用本文： | 杨树俊,王浩.纳米载体应用于透皮给药系统的研究进展[J].中国医药工业杂志,2011,42(7). |
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| 作者姓名： | 杨树俊 王浩 |
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| 作者单位： | 中国医药工业研究总院药物制剂国家工程研究中心,上海,201023 |
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| 摘 要： | 纳米载体经皮给药系统是近几年经皮给药的研究热点。本文综述了各种纳米载体在经皮给药系统中应用的研究进展,其中囊泡、微乳和固体脂质纳米粒作为经皮给药载体已得到相对深入的研究,而新型纳米载体如胶束、树状大分子和细胞促透多肽等尽管研究较少,但基于其明显的促渗作用,将会为经皮给药系统的研究提供新方向。
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| 关 键 词： | 纳米载体 经皮给药系统 综述 |
Progress in Research of Nano-sized Carriers for Transdermal Drug Delivery System |
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| Authors: | YANG Shujun WANG Hao |
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| Institution: | YANG Shujun,WANG Hao~* (National Pharmaceutical Engineering and Research Center,China State Institute of Pharmaceutical Industry,Shanghai 201205) |
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| Abstract: | A lot of researchers focus on the application of nano-sized carriers for trandermal drug delivery system(TDDS) recently.The progress in nano-sized carriers for TDDS,including vesicles,microemulsions,solid lipid nanoparticles,micelles,dendrimers,electrospinning nanofibers,etc is reviewed.Vesicles,microemulstions and solid lipid nanoparticles have been intensively studied as nano-sized carriers for TDDS.Although the innovative nano-carriers,such as micelles,dendrimers and cell-penetrating peptides,do not beco... |
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| Keywords: | nano-sized carrier transdermal drug delivery system review |
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