| 高效液相色谱法测定六味地黄丸的溶出度 |
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| 引用本文： | 韩玲玲,胡容峰. 高效液相色谱法测定六味地黄丸的溶出度[J]. 中国实验方剂学杂志, 2007, 13(4): 8-10 |
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| 作者姓名： | 韩玲玲 胡容峰 |
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| 作者单位： | 安徽中医学院,安徽,合肥,230038 |
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| 基金项目： | 安徽省教育厅自然科学研究项目（2006kj337B） |
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| 摘 要： | 目的：测定六味地黄丸中丹皮酚和马钱苷的溶出度。方法：采用溶出度第三法（小杯法）测定六味地黄丸的溶出度,以高效液相色谱法测定其浓度。结果：马钱苷24 h的平均累积溶出百分率为94.42%,丹皮酚24 h平均累积溶出百分率为68.75%。结论：该方法准确、可靠,可同时用于测定六味地黄丸中的两种成分的溶出情况。
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| 关 键 词： | 高效液相色谱法 溶出度 马钱苷 丹皮酚 |
| 文章编号： | 1005-9903（2007）04-0008-03 |
| 收稿时间： | 2006-08-01 |
| 修稿时间： | 2006-08-01 |
Determination of Dissolution of Liuwei Dihuang Wan by HPLC |
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| HAN Ling-ling,HU Rong-feng. Determination of Dissolution of Liuwei Dihuang Wan by HPLC[J]. China Journal of Experimental Traditional Medical Formulae, 2007, 13(4): 8-10 |
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| Authors: | HAN Ling-ling HU Rong-feng |
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| Affiliation: | Anhui Colege Of Traditional Chinese Medicine, Hefei, Anhui, China, 230038, China |
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| Abstract: | Objective:To investigate the dissolution of Loganin and paeonol of Liuwei Dihuang Wan.Methods:The third method was used to determine the dissolution of Liuwei Dihuang Wan.A HPLC method was established for the determination of dissolution of Loganin and paeonol.Results: The accumulated release rate of Loganin at 24 hours was 94.42%,The accumulated release rate of paeonol at 24 hours was 68.75%.Conclusion:The method is accurate and reliable.It can be used for the determination of dissolution of Liuwei Dihuang Wan. |
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| Keywords: | HPLC dissolution Ioganin paeonol |
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