Diffusion tensor imaging of the brain: review of clinical applications

Abstract We review the theoretical background to diffusion tensor imaging (DTI) and some of its commoner clinical applications, such as cerebral ischemia, brain maturation and traumatic brain injury. We also review its potential use in diseases such as epilepsy, multiple sclerosis, and Alzheimers disease. The value of DTI in the investigation of brain tumors and metabolic disorders is assessed.