冠心病心室晚电位与冠状动脉病变的关系

为观察心室晚电位（ＶＬＰ）、心律失常事件（ＡＥ）与冠状动脉病变的关系，对１４５例冠心病患者（心绞痛５５例、陈旧性心肌梗死９０例）进行信号平均心电图的定性分析和２４小时Ｈｏｌｔｅｒ监测，并同期进行冠状动脉造影，并长期随访观察。１１９例（失访２６例）随访１４．１±７．１（４～３６）个月，发生ＡＥ７例。ＶＬＰ阳性者ＡＥ发生率２５％（４／１６），明显高于ＶＬＰ阴性者ＡＥ的发生率２．９％（３／１０３），Ｐ＜０．００１；ＶＬＰ、ＡＥ与冠状动脉病变血管的支数和狭窄程度之间均无明显关系（Ｐ均＞０．０５）。结果提示ＶＬＰ与ＡＥ密切相关，但ＶＬＰ、ＡＥ与冠状动脉病变的范围和程度无明显关系。

Relations Between Ventricular Late Potentials and Coronary Artery Lesionin Patients With Coronary Artery Disease

To observe relations between ventricualr late potentials (VLP),arrhythmic events (AE) and coronary artery lesion,the signal averaged electrocardiogram was prospectively assessed in 145 patients with coronary artery disease by qualitative analysis and 24 hours Holter monitoring were recorded,the coronary artery angiography was performed in all cases at the same period and the long term follow up was performed.In 145 patients with coronary artery disease(55 patients with angina pectoris,90 patients with old myocardial infaction),arrhythmic events occurred in 7 patients during 14.1±7.1(4～36) months follow up period.25% of VLP positive cases had AE,compared with 2.9% of VLP negative cases (P<0.001).Neither VLP nor AE had relation to the numbers and the narrowing degree of diseased coronary artery (P>0.05 ,respectively).The results means that VLP has a close relation to arrhythmic events,and neither VLP nor AE has relation to extent and degree of coronary artery lesion.