| 大鼠死后胸主动脉生物力学特征变化规律的研究 |
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| 引用本文： | 张付,周睿卿,陈晓刚,廖志钢.大鼠死后胸主动脉生物力学特征变化规律的研究[J].生物医学工程学杂志,2008,25(4):849-851. |
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| 作者姓名： | 张付 周睿卿 陈晓刚 廖志钢 |
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| 作者单位： | 四川大学,华西基础医学与法医学院,成都,610041 |
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| 摘 要： | 取死后0～7 d大鼠胸主动脉进行单轴拉伸实验,观察各力学指标随死后经过时间(Post mortem interval,PMI)延长的演变,选取有明显变化趋势的力学指标进行统计分析.力学指标中最大值应力、最大值应变、能量与PMI有显著相关,其决定系数(R2)分别为0.822、0.716、0.669(P＜0.001).表明运用拉伸实验测量胸主动脉生物力学指标的变化可用于PMI推断.
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| 关 键 词： | 死后经过时间 胸主动脉 拉伸 |
An Experimental Study on the Changes in the Biomechanical Characters of Rat Thoracic Aorta |
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| Zhang Fu,Zhou Ruiqing,Chen Xiaogang,Liao Zhigang.An Experimental Study on the Changes in the Biomechanical Characters of Rat Thoracic Aorta[J].Journal of Biomedical Engineering,2008,25(4):849-851. |
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| Authors: | Zhang Fu Zhou Ruiqing Chen Xiaogang Liao Zhigang |
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| Institution: | West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China. |
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| Abstract: | The changes in biomechanics of rat thoracic aorta at different post mortem interval (PMI) (0-7 d) were observed when it was stretched in one direction. Some significant changes were disclosed by statistical analyses. Maximum stretch, maximum strain and maximum energy showed a significant relationship with PMI, the coefficients of determination being 0.822, 0.716 and 0.669 respectively, P < 0.001. The stretch experiment of thoracic aorta may be a novel method to determine PMI. |
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