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Coronary atherosclerosis in anorexia nervosa
Authors:Birmingham Carl Laird  Lear Scott A  Kenyon Jennifer  Chan Sammy Yat Man  Mancini G B John  Frohlich Jiri
Institution:Eating Disorders Program, St. Paul's Hospital, University of British Columbia, Vancouver, Canada. clbirm@interchange.ubc.ca
Abstract:BACKGROUND: Chest pain is a common complaint in patients with anorexia nervosa (AN). Of those who experience chest pain, about 20% meet the diagnostic criteria for typical or atypical angina. METHODS: We compared the intima-medial thickness (IMT) of the carotid artery measured by ultrasound in AN with controls and found no difference. RESULTS AND DISCUSSION: Although clinically relevant atherosclerosis can occur in patients with a normal IMT, there is a strong correlation between carotid IMT and coronary atherosclerosis. This suggests that an atherosclerotic origin of chest pain in AN patients is unlikely.
Keywords:coronary atherosclerosis  atherosclerosis  anorexia nervosa  eating disorders  mortality
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