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Hypolipidaemic Activity of Ficus carica Leaf Extract in Streptozotocin-diabetic Rats
Authors:E. Dominguez  J. R. Canal  M. D. Torres  J. E. Campillo  C. Perez
Abstract:A decoction of Ficus carica significantly lowered plasma triglyceride levels in rats with insulin-dependent diabetes (streptozotocin 80 mg/kg body weight) when it was administered orally (357±206 mg/dL before administration and 81±81 mg/dL 3 weeks after administration, p< 0.01, n =11). The plasma triglyceride levels in diabetic rats were also lower when the Gicus carica extract was administered intraperitoneally (608±391 mg/dL before administration; 444±310 mg/dL 90 min after administration; and 106±129 mg/dL 48 h after administration; p< 0.005, n =7). The cholesterolaemia remained unchanged.
Keywords:hypolipidaemic activity  Ficus carica extract  streptozotocin-diabetic rats
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