C反应蛋白与急性冠脉综合征

动脉粥样硬化是一种炎症性病变,急性冠脉综合征的发生、发展更与炎症密切相关。C反应蛋白是一种典型的炎症急性相反应蛋白,其血浆水平的高低可直接反映冠状动脉粥样硬化斑块的炎症状态及稳定程度。目前,把血浆C反应蛋白作为急性冠脉综合征患者危险分层和预后判定指标的临床价值已逐渐得到认同,但最新研究发现,新蝶呤和脑利钠肽等对急性冠脉综合征患者的预后评估可能较C反应蛋白更为特异而敏感。

C-Reactive Protein and Acute Coronary Syndrome

Atherosclerosis(AS) is a inflammatory pathological changes.The occurrence and development of acute coronary syndrome(ACS) nearly correlate with inflammation.The C-reactive protein(CRP) is a typically acute reactive protein,the level of which in plasma concentration can directly show the inflammatory state of atherosclerotic plaque and the degree of stabilization.It is gradually accepted that CRP can act as a indication of risk stratification and values in outcome to ACS patients.But recently study suggests that neopterin and brain natriuretic peptide are more different and sensitive than it.