Acylcarnitine profile in thyroid disease |
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| Authors: | Sophia Wong Fady Hannah-Shmouni Graham Sinclair Sandra Sirrs Marshall Dahl Andre Mattman |
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| Affiliation: | 1. Centro de Química Inorgánica (CEQUINOR/CONICET/UNLP)-Facultad de Ciencias Exactas, Universidad Nacional de La Plata, 47 esq 115, 1900 La Plata, Argentina;2. Departamento de Química Inorgánica, Facultad de Ciencia y Tecnología, Universidad del País Vasco, Apdo 644, 48080 Bilbao, Spain;3. Departamento de Fisiología, Universidad de Alcalá, Campus Universitario, 28871-Alcalá de Henares, Madrid, Spain |
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| Abstract: | ObjectivesTo examine acylcarnitine profiles in individuals with hypo- or hyperthyroidism, and determine whether any atypical acylcarnitine species identified would normalize with correction of thyroid status.Design and methodsSerum acylcarnitine levels were measured in hypo- and hyperthyroid subjects before and after treatment with thyroxine or thionamide therapy respectively.ResultsNo discernible differences were observed in the serum acylcarnitine profiles between hypo-, hyper- and euthyroid states.ConclusionsAcylcarnitine profiles are relatively unremarkable in thyroid disease. |
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