| 电刺激大鼠右侧尾壳核诱导皮层脑电高频振荡的特征 |
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| 引用本文： | 韩娟,李永格.电刺激大鼠右侧尾壳核诱导皮层脑电高频振荡的特征[J].癫癎与神经电生理学杂志,2021(1):6-9. |
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| 作者姓名： | 韩娟 李永格 |
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| 作者单位： | 河南省南阳市第二人民医院神经内科;河南省南阳医学高等专科学校基础医学部 |
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| 基金项目： | 河南省高等学校重点科研项目(NO:15B310009);河南省高等学校青年骨干教师培养计划(NO:2018GGJS253)。 |
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| 摘 要： | 目的 探讨电刺激大鼠右侧尾壳核诱导皮层脑电高频振荡(HFO)功率谱特征.方法 实验共用雄性SD大鼠56只,体质量150?250 g,氨基甲酸乙酯麻醉下行气管插管和开颅术.将一根双极不锈钢同芯刺激电极植于右侧尾壳核,重复施加电刺激(60 Hz,2 s,0.4?0.6 mA);将两个不锈钢螺丝钉旋入双侧皮层的颅骨内,一个不...
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| 关 键 词： | 脑电图 高频电振荡(HFO) 功率谱 皮层 大鼠 |
The properties of the power spectrum of neocortical high frequency oscillations induced by acute tetanization of the right caudate putamen nucleus |
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| HAN Juan,LI Yongge.The properties of the power spectrum of neocortical high frequency oscillations induced by acute tetanization of the right caudate putamen nucleus[J].Journal of Epileptology and Electroneurophysiology(CHINA),2021(1):6-9. |
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| Authors: | HAN Juan LI Yongge |
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| Institution: | (Department of Neurology,the Second People's Hospital of Nanyang City,Nanyang(473000),Henan China) |
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| Abstract: | Objective To study the electrophysiological properties of the power spectrum of neocortical high frequency oscillations(HFOs)induced by acute tetanization(60 Hz,2 s,0.4~0.6 mA)of the right caudate putamen nucleus(ATRC).Methods Experiments were performed on 56 male rats,weighed 150~250 g.Rats were anaesthetized with 10% urethane(1g/kg,ip)endotracheally intubated and monunted in a stereotaxic apparatus.Three stainless screws were fixed on cranial bones were used for EEG recording of the surface of bilateral neocoties and one reference point on cranial bones over the surface of cerebellar cortex.Results 80~450 Hz oscillation patterned in waxing and waning;The ripple duration time was about HFO with10 ms.The contralateral oscillation became much stronger and the latent period was shortened.Conclusion ATRC can induce HFOs reflecting a Cpu-neocortical epilepsy network reorganization. |
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| Keywords: | EEG neocortical high frequency oscillations(HFO) power spectrum neocortex rat |
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