The effects of malaria and HIV co-infection on hemoglobin levels among pregnant women in Sekondi-Takoradi,Ghana |
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Authors: | Verner N. Orish Onyekachi S. Onyeabor Johnson N. Boampong Samuel Acquah Adekunle O. Sanyaolu Nnaemeka C. Iriemenam |
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Affiliation: | 1. Department of Internal Medicine, Effia-Nkwanta Regional Hospital Sekondi-Takoradi, Sekondi-Takoradi, Ghana;2. Satcher Health Leadership Institute, Department of Community Health and Preventive Medicine, Morehouse School of Medicine, Atlanta, USA;3. Department of Human Biology, University of Cape Coast, Cape Coast, Ghana;4. Department of Medical Biochemistry, School of Medical Sciences, University of Cape Coast, Cape Coast, Ghana;5. Department of Medical Microbiology and Parasitology, College of Medicine of the University of Lagos, Idi-Araba, Lagos, Nigeria;6. Saint James School of Medicine, Anguilla |
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Abstract: | ObjectiveTo assess the burden of maternal malaria and HIV among pregnant women in Ghana and to determine the risk of anemia among women with dual infection.MethodsA cross-sectional study was conducted at 4 hospitals in the Sekondi-Takoradi metropolis, Ghana. The study group comprised 872 consenting pregnant women attending prenatal care clinics. Venous blood samples were screened for malaria, HIV, and hemoglobin level. Multivariate logistic regression analysis was performed to determine the association between malaria, HIV, and risk of anemia.ResultsIn all, 34.4% of the study cohort had anemia. Multivariate logistic regression analysis indicated that pregnant women with either malaria (odds ratio 1.99; 95% confidence interval, 1.43–2.77; P = < 0.001) or HIV (odds ratio 1.78; 95% confidence interval, 1.13–2.80; P = 0.014) had an increased risk of anemia. In adjusted models, pregnant women co-infected with both malaria and HIV displayed twice the risk of anemia. The adjusted odds ratio was 2.67 (95% confidence interval, 1.44–4.97; P = 0.002).ConclusionPregnant women infected with both malaria and HIV are twice as likely to be anemic than women with a single infection or no infection. Measures to control malaria, HIV, and anemia during pregnancy are imperative to improve birth outcomes in this region of Ghana. |
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