Microinjected Coxsackie B1 virus does not replicate in HEp-2 cells. |
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| Authors: | K R Modalsli G Bukholm S O Mikalsen M Degré |
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| Institution: | Kapt. W. Wilhelmsen og Frues Bakteriologiske Institutt, University of Oslo, Rikshospitalet, Norway. |
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| Abstract: | Coxsackie B1 virus did not replicate when microinjected into HEp-2 cells. Replication was assayed by production of infectious virus particles, synthesis of viral RNA, and lysis of cells. The same virus preparation initiated replication when it was inoculated into HEp-2 cells similarly to that by microinjected purified coxsackie B1 virus RNA. |
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