序贯治疗老年人下呼吸道感染四种方案的药物经济学分析

目的 探讨不同抗菌药物序贯治疗老年人下呼吸道感染的经济效果。方法 选择92例下呼吸道感染的60例以上老年病人，采用4种不同的药物序贯治疗方案(A组：阿莫西林组；B组：头孢拉定组；C组：左旋氧氟沙星组；D组：阿奇霉素组)，运用药物经济学成本-效果分析方法进行评价。结果 4种治疗方案总成本依次为258．40元、386．80元、369．70元、792．30元，其总有效率分别为83．3％、92．3％、85．0％、90．1％。结论 头孢拉定组(B组)方案为老年人下呼吸道感染的较佳治疗方案。

Pharmacoeconomic analysis of four different sequential antimicrobial therapy for lower respiratory tract infections in old people

Objective To study the economic efficiency of different sequential antimicrobial therapy(SAT) in treatment of lower respiratory tract infections(LRTI) in old people.Methods Ninety-two old patients over sixty years with LRTI were divided into 4 groups.They received different SAT(A:amoxicillin;B:cefradine;C:levofloxacin;D:azithromycin).Evaluation was carried out with pharmacoeconomic cose-effectiveness analysis(CEA).Results The costs of A,B,C and D schemes were RMB 258.40,386.80,369.70 and 792.30 yuans,respectively,and the effective rates were 83.3%,92.3%,85.0% and 90.1%,respectively.Conclusion The therapeutic scheme of B seems to be the best one for treating LRTI in old people.