前列腺磁共振检查患者1 066例临床情况分析

目的:总结北京大学第一医院近12年来进行前列腺磁共振(magnetic resonance,MR)检查患者的临床情况及检查目的的变化.方法:回顾性分析了我院1992年5月至2004年9月所有进行前列腺MR检查的1 066例(1 296人次)患者的临床资料,统计每年行前列腺MR检查患者病例数,根据检查目的进行分组,并着重分析初次就诊组患者当时的年龄、临床症状、血清前列腺特异性抗原(prostate specific antigen,PSA)浓度、超声或直肠指检(digital rectal examination,DRE)有无结节等的变化趋势.结果:(1)近12年来,年均前列腺MR检查人数逐渐增加,并且是以定性诊断为目的患者增加为主.(2)以定性诊断为目的患者中具有良性前列腺增生(benign prostate hyperlasia,BPH)症状患者所占比例逐年增加,因发现血清PSA浓度升高、前列腺结节及因出现前列腺癌转移症状就诊患者所占比例逐年减少,因其他相关前列腺症状就诊患者所占比例变化不明显.结论:随着前列腺疾病筛查工作的开展,越来越多的早期前列腺癌和非前列腺癌患者接受MR检查,对MR检查提出了更高的要求.

Analysis of the clinical information of 1 066 cases undergoing prostate magnetic resonance examination

Objective:To evaluate the variation of clinical data and referred purpose of prostate magnetic resonance(MR) examination in the past 12 years in Peking University First Hospital.Methods:One thousand and sixty-six patients underwent prostate MR examination(1 296 exams) from May 1992 to Sept.2004.The clinical data of the patients were retrospectively analyzed.The number of patients was counted and three groups were classified(diagnosing group,staging group and follow-up group) according to the purpose of prostate MR examination per year.For the diagnosing group, the clinical data of patient's age,symptom,level of serum prostate specific antigen(PSA),and the result of ultrasound or digital rectal examination(DRE) were evaluated.Results:(1)The number of patients increased year by year in the past 12 years,and the majority of the increased patients required differential diagnosis.(2) Diagnosing group: the percentage of patients with the symptom of BPH increased year by year.The average level of serum PSA dropped and the percentage of patients with elevated PSA or with nodules detected by ultrasound or DRE referred for detection of prostate cancer or with the symptom of metastasis decreased.Conclusion:With the widespread screening of prostate cancer,more patients of early prostate carcinoma and non-tumoral lesion in prostate gland are examined by MR imaging.