| 丙烯腈对血液胆碱酯酶活性影响的研究 |
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| 引用本文： | 肖卫.丙烯腈对血液胆碱酯酶活性影响的研究[J].兰州医学院学报,1999,25(1):4-6. |
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| 作者姓名： | 肖卫 |
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| 作者单位： | 兰州医学院劳动卫生与职业病学教研室 |
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| 摘 要： | 目的 通过对丙烯腈作业工人及实验动物全血胆碱酯酶活性的测定，揭示丙烯腈对血液胆碱酯酶活性的影响，更全面认识丙烯腈的毒性。方法 采集职业人群及实验动物的全血，分别测定其中胆碱酯酶活性，并比较分析。结果 接触组工人全血胆碱酯酶活性明显低于对照组（Ｐ〈０．０１），且随丙烯腈浓度的升高，全血胆碱酯酶活性下降更明显。动物实验也有相似结果。结论 对职业人群和实验动物，丙烯腈均有降低全血胆碱酯酶活性的作用。
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| 关 键 词： | 丙烯腈 胆碱酯酶活性 血液 职业危害 |
Effects of acrylonitrile on activity of blood cholinesterase |
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| XIAO Wei.Effects of acrylonitrile on activity of blood cholinesterase[J].Journal of Lanzhou Medical College,1999,25(1):4-6. |
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| Authors: | XIAO Wei |
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| Institution: | XIAO Wei.Department of Labor
Health,Lanzhou Medical College,Lanzhou 730000 |
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| Abstract: | bjective To recognize the toxic effects
of
acrylonitrile by studying the activity of blood cholinesterase of workers and rats exposed to
acrylonifrile. MethodsBZCollected the blood of exposed workers and rats,and assaied the activity
of the blood cholinesterase.ZResults The activity of blood cholinesterase is much lower in
exposed workers(P<0.01),and it has the doseresponse relationship. Conclusions Acrylonitrile
reduces the activity of blood cholinesterase. |
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| Keywords: | AcrylonitrileBloodCholinesterase |
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