Comparative researches on effects of sodium dodecylbenzene sulfonate and sodium dodecyl sulfate upon Lateolabrax japonicus biomarker system |
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| Affiliation: | 1. TCM and Ethnomedicine Innovation & Development Laboratory, School of Pharmacy, Hunan University of Chinese Medicine, Changsha, China;2. National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, University of Mississippi, MS, USA;3. Department of Pharmacognosy, School of Pharmacy, University of Mississippi, MS, USA;4. Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia;1. Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta T6G 2V4, Canada;2. Department of Electrical and Computer Engineering, University of Alberta, Edmonton, Alberta T6G 2V4, Canada;3. Suncor Energy Inc., Fort McMurray, Alberta T9H3E3, Canada |
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| Abstract: | Fish Lateolabrax japonicus were exposed to anion surfactant sodium dodecylbenzene sulfonate (SDBS) and sodium dodecyl sulfate (SDS) at 1 mg/l, respectively, for 6, 12 and 18 d, with one control group. Liver antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH) and glutathione S-transferase (GST) were determined; brain acetylcholinesterase (AChE) and liver inducible nitric oxide synthase (iNOS) activities were also measured. The results of the study indicated that these parameters made different, sometimes, adverse responses to SDBS and SDS exposure, such as the activity of iNOS can be inhibited by SDBS and induced by SDS, the different physico-chemical characteristics of SDBS and SDS should be responsible for their effects on enzyme activities. |
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