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Cardiometabolic Indices after Weight Loss with Calcium or Dairy Foods: Secondary Analyses from a Randomized Trial with Overweight/Obese Postmenopausal Women
Authors:Jasminka Z. Ilich  Pei-Yang Liu  Hyehyung Shin  Youjin Kim  Yichih Chi
Affiliation:1.Institute for Successful Longevity, Florida State University, Tallahassee, FL 32306, USA;2.School of Exercise and Nutrition Sciences, University of Akron, Akron, OH 44325, USA;3.Department of Social Welfare, Pusan National University, Pusan 46241, Korea;4.GNC Holdings, LLC, Pittsburg, PA 15222, USA;5.Independent Researcher, Fremont, CA 94539, USA;
Abstract:The role of dairy foods and calcium/vitamin D supplements in cardiometabolic diseases is unknown. The objective of this secondary analysis is to investigate cardiometabolic risk factors changes after a 6-month weight-loss intervention in overweight/obese postmenopausal women divided in three groups: Ca+vitamin D supplements (S); low-fat dairy foods (D; 4–5 servings/day); or control/placebo pills (C), as complements to hypocaloric diets. The original study focused on bone/body composition. This analysis included blood pressure (BP), and serum triglycerides, lipids (including apoproteins Apo1 and ApoB), adipokines, and C-reactive protein in n = 97 participants who finished with complete data points. Systolic BP decreased 5.1%, 4.8%, and 1.8% in S, D, and C groups, respectively (p < 0.05 for S and D vs. baseline and vs. C at 6 months). Reduction in triglycerides and ratio of total cholesterol (TC)/high-density lipoproteins cholesterol (HDL-C) was the highest in S, while the reduction in TC and LDL-C was the highest in D group (all p < 0.05). Leptin and ApoB significantly decreased and adiponectin and ApoA1 increased in all groups. In conclusion, although the C group’s participants experienced an improvement in some of the cardiometabolic indices with weight loss, those in the S and D groups showed significantly better results in most of the outcomes, indicating the beneficial effects of low-fat dairy foods and/or Ca+vitamin D intake as complements to a hypocaloric diet.
Keywords:calcium and vitamin D supplements   low-fat dairy foods   cardiometabolic risk factors   weight loss   blood pressure   serum apolipoproteins   adipokines   serum vitamin D
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